From Genome Analysis Wiki
Jump to navigationJump to search
80 bytes added
, 18:54, 10 April 2014
Line 11: |
Line 11: |
| * NOTE: current version can only process one chromosome at a time | | * NOTE: current version can only process one chromosome at a time |
| | | |
− | * vcf2map | + | * vcf2map: generate a sparse map file |
| vcf2map --vcf input.vcf --ped input.ped --map genetic_map_GRCh37_chr1.txt --include_list 1000G.SNV.clean.MAF0.05.tbl.gz --out_map chr1.map | | vcf2map --vcf input.vcf --ped input.ped --map genetic_map_GRCh37_chr1.txt --include_list 1000G.SNV.clean.MAF0.05.tbl.gz --out_map chr1.map |
| vcf2map --vcf input.vcf --ped input.ped --map genetic_map_GRCh37_chr1.txt --include_list 1000G.SNV.clean.MAF0.05.tbl.gz --max_r2 0.2 --min_avg_dp 2 --out_map chr1.r0.2.map | | vcf2map --vcf input.vcf --ped input.ped --map genetic_map_GRCh37_chr1.txt --include_list 1000G.SNV.clean.MAF0.05.tbl.gz --max_r2 0.2 --min_avg_dp 2 --out_map chr1.r0.2.map |
| | | |
− | * polymutt2 | + | * polymutt2: taking a VCF and the map file generated by vcf2map |
| polymutt2 -p input.ped -m chr1.map --in_vcf input.vcf --out_vcf out.vcf | | polymutt2 -p input.ped -m chr1.map --in_vcf input.vcf --out_vcf out.vcf |
| polymutt2 -p input.ped -m chr1.map --in_vcf input.vcf --out_vcf out.vcf --best_path | | polymutt2 -p input.ped -m chr1.map --in_vcf input.vcf --out_vcf out.vcf --best_path |