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| style="width:100%; text-align:center; white-space:nowrap; color:#000;" | <div style="font-size:162%; border:none; margin:0; padding:.1em; color:#000;">Abecasis Group Wiki</div>
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[[Image:AbecasisRetreat2016.jpg|700px|center|Group Photo 2016]]
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== Welcome!  ==
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Welcome to our wiki!
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If you would like to contribute, [[Special:UserLogin|log-in]] or [[Special:RequestAccount|request an account]]. We recommend using your e-mail address or Michigan uniqname as your user id.
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For basic instructions, see [http://en.wikipedia.org/wiki/Wikipedia:Tutorial the Wikipedia Tutorial].
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== Sequence Analysis Tools  ==
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We are developing [[Software|software tools]] for the analysis of next generation sequence data.
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These tools include:
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#Variant Calling with [[GlfSingle]] and [[GlfMultiples]]
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#Variant Calling and De Novo Mutation Detection in Families with [[Polymutt]]
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#Variant Annotations using [[VcfCodingSnps]]
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#Rare Variant Analysis using [[RvTests]]
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#Rare Variant Association Analysis in family samples [[FamRvTest]]
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#Quality control using [[C++ Executable: fastQValidator|FastQValidator]], [[VerifyBamID]], and [[BamValidator]]
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#C++ APIs for sequence analsysis using [[C++ Library: libStatGen]]
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#Meta-analysis of single variant or gene-level associations [[RAREMETAL-SOFTWARE]]
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#Sequencing study design helper [[Rarefy]]
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#Local ancestry inference (ancestry painting) using off-targeted sequence data [[SEQMIX]]
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#Association Container Toolbox [[EPACTS]]
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#Fast Genotype Imputation Tool : [[Minimac3]]
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These tools and additional tools can be found on the [[Software]] page.
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We are developing Genome/Sequencing Processing Pipelines for anyone to use: [[GotCloud]]
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== High Level Tutorials  ==
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Some high-level tutorials on the analysis of next generation sequence data:
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#[[Evaluating a Read Mapper on Simulated Data]]
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#[[SNP Call Set Properties]]
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#[[Generic Exome Analysis Plan]]
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== Projects  ==
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[[NHLBI Informatics Resource|NHLBI Genome Sequencing Project]]
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[[SardiNIA]] - The SardiNIA longitudinal study of aging.
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[[EMADS|Exome Meta-analysis of Drinking and Smoking (EMADS)]]
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[http://www.1000genomes.org The 1000 Genomes Project]
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== Learn Genetics  ==
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Faculty in the group teach in a variety of formal and informal settings. [[Class Notes|Class notes]] and relevant discussion are archived here.
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== General Resources  ==
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*[[Computer How-Tos]]
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