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, 18:05, 10 February 2011
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| This page documents how to impute 1000 Genome SNPs using | | This page documents how to impute 1000 Genome SNPs using |
− | * MaCH (concurrent phasing approach) | + | * MaCH (concurrent phasing approach). |
| * or minimac (pre-phasing approach). | | * or minimac (pre-phasing approach). |
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| + | == Shoud I use MaCH or minimac? |
| + | The imputation quality of both approaches is comparable. |
| + | If you are carrying out only an one-time imputation and you are focusing only on autosomes - then go with MaCH. |
| + | If you are planning to re-impute into new reference panels and your are interested into the X-chromosome - then minimac is the right choice for you. |
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