Changes

= Genomes on the Cloud (GotCloud)=

= Genomes on the Cloud (GotCloud)=

To handle the increasing volume of next generation sequencing and genotyping data, we created and developed software pipelines called '''Genomes on the Cloud (GotCloud)''' for:

To handle the increasing volume of next generation sequencing and genotyping data, we created and developed software pipelines called '''Genomes on the Cloud (GotCloud).'''

 

*Variant Calling

GotCloud contains Mapping & Variant Calling Pipelines.

Key Features:

Key Features:

*Scalable to tens of thousands of samples

* Connects sequence analysis tools together in automated pipeline

*Robust against unexpected system failure using GNU make

* Robust against unexpected system failure using GNU make

** easy restart after failure

** easy restart after failure

*Massively parallel, can run hundreds of jobs

* Massively parallel, can run hundreds of jobs

** Splits large jobs into many pieces

** Splits large jobs into many pieces

*Easy to use - Automates series of configurable steps

*Available on Amazon Web Services (AWS) Elastic Compute Cloud (EC2)

*Run on local machines/clusters

* Easy to use - Automates series of configurable steps so the user doesn't have to understand/configure/know the many tools required to create high quality results

*Available via Debian Packages

* Available on Amazon Web Services (AWS) Elastic Compute Cloud (EC2)

* Run on local machines/clusters

* Available via Debian Packages

Takes pipelines we have been using for our sequence data processing and makes them publicly available & usable.

The pipelines in GotCloud have been used for our sequence data processing and are now publicly available.

 

but you can just as easily use the pipelines on your own machine(s) by just installing them.

 

[[File:GotCloudDiagram.png]]

[[File:GotCloudDiagram.png]]