Changes

From Genome Analysis Wiki
Jump to navigationJump to search
Line 10: Line 10:  
== Parsimony ==
 
== Parsimony ==
   −
This refers to the representation of a variant in as few nucleotides as possible.  A representation with nucleotides that can be inferred from the reference sequence is not considered parsimonious.  The blue variant representation in the figure is not parsimonious because the second CA can be inferred from the reference sequence.  The maroon representation is parsimonious, the alternate allele contains only a single base from the reference sequence.
+
This refers to the representation of a variant in as few nucleotides as possible.  For insertions, a representation with more than a single reference nucleotide is not considered parsimonious.  For deletions, a representation with more than a single alternate nucleotide is not considered parsimonious.  For the insertion in the figure above, the blue representation is not parsimonious because the second CA can be inferred from the reference sequence.  The maroon representation is parsimonious, the alternate allele contains only a single base from the reference sequence.
    
== Left alignment ==
 
== Left alignment ==
66

edits

Navigation menu