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| [[Rarefy|'''rarefy''']] is a tool to help selecting informative families and individuals from a sample. It takes account pedigree structure and calculates an informative score for each individual to evaluate the potential of carrying trait-influencing rare variants. It has been used for selecting individuals in Minnesota Twins substance abuse whole-genome sequencing project and SardiNia deep sequencing project. | | [[Rarefy|'''rarefy''']] is a tool to help selecting informative families and individuals from a sample. It takes account pedigree structure and calculates an informative score for each individual to evaluate the potential of carrying trait-influencing rare variants. It has been used for selecting individuals in Minnesota Twins substance abuse whole-genome sequencing project and SardiNia deep sequencing project. |
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− | [[FamRvTest|'''famRvTest''']] is an efficient tool for rare variant association analysis. It handles related individuals and study specific covariates. The tool supports both single variant and gene-level associations. It has been used in eQTL and quantitative traits association analysis in T2Dgenes project. | + | [[FamRvTest|'''famRvTest''']] is an efficient tool for rare variant association analysis. It handles related individuals and study specific covariates. The tool supports both single variant and gene-level associations with various methods implemented. It has been used in eQTL and quantitative traits association analysis in T2Dgenes project. |
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| [[RAREMETALWORKER|'''raremetalworker''']] is a tool to generate summary statistics for meta-analysis of rare variants using raremetal. It handles both related and unrelated individuals. | | [[RAREMETALWORKER|'''raremetalworker''']] is a tool to generate summary statistics for meta-analysis of rare variants using raremetal. It handles both related and unrelated individuals. |
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| [[RAREMETAL|'''raremetal''']] is a tool for meta-analysis of rare variants. It supports both single variant and gene-level tests. | | [[RAREMETAL|'''raremetal''']] is a tool for meta-analysis of rare variants. It supports both single variant and gene-level tests. |