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Created page with 'The '''GENOMICCONTROL''' setting defaults to off, which means that no correction is applied to input studies. Setting <code>GENOMICCONTROL ON</code> requests that METAL should a…'
The '''GENOMICCONTROL''' setting defaults to off, which means that no correction is
applied to input studies. Setting <code>GENOMICCONTROL ON</code> requests that
METAL should automatically calculate and apply an appropriate genomic control
correction to each study.

Newer versions of METAL also now allow for a specific genomic control parameter
as input. In this case, instead of automatically calculating the GENOMICCONTROL
value based on available data, METAL will apply the correction according to a
user-specified parameter. This option is convenient when full genome scan results
are not included in METAL input files.

Example:

GENOMICCONTROL 1.1

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