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, 15:19, 19 February 2014
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| This figure shows multiple representations of a MNP. The left shows 4 possible representations differentiated by color. The right shows the corresponding representation in VCF. The last representation represents the parsimonious representation of the MNP. | | This figure shows multiple representations of a MNP. The left shows 4 possible representations differentiated by color. The right shows the corresponding representation in VCF. The last representation represents the parsimonious representation of the MNP. |
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− | We would like to represent a variant in as few nucleotides as possible. Taking the example above, the MNP is represented superfluously for the first 3 representations and parsimoniously for the 4th representation. When a variants has superfluous nucleotides on the left side, we refer that as a need to left trim and similarly for right trimming. | + | We would like to represent a variant in as few nucleotides as possible. Taking the example above, the MNP is represented superfluously for the first 3 representations and parsimoniously for the 4th representation. When a variant has superfluous nucleotides on the left side, we refer that as a need to left trim and similarly for right trimming. |
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| == Left alignment == | | == Left alignment == |