Uploads by Goncalo
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| Date | Name | Thumbnail | Size | Description | Versions |
|---|---|---|---|---|---|
| 01:16, 11 February 2010 | 666.07.pdf (file) |  |
344 KB | Advanced lecture on the coalescent by guest lecturer, Sebastian Zoellner. Focused on coalescent modeling with changing population sizes. February 2, 2009. | 1 |
| 01:17, 11 February 2010 | 666.08.pdf (file) | |
423 KB | Advanced guest lecture by Sebastian Zoellner. Focused on computation methods related to the coalescent. February 4, 2010. | 1 |
| 07:17, 18 March 2010 | 666.14.pdf (file) | |
1.7 MB | 1 | |
| 07:09, 23 March 2010 | 666.15.pdf (file) | |
1.02 MB | Shows how a simple disease model can be used to predict IBD probabilities for relative pairs. Introduces possible triangle constraint. | 1 |
| 00:50, 1 April 2010 | 666.18.pdf (file) | |
736 KB | Introduces the Lander-Green algorithm. | 1 |
| 00:54, 8 April 2010 | 666.19.pdf (file) | |
1.24 MB | 3 | |
| 00:09, 14 April 2010 | LocusZoomSmall.png (file) |  |
47 KB | 1 | |
| 10:06, 20 April 2010 | 666.21.pdf (file) | |
1.89 MB | 2 | |
| 09:09, 22 July 2010 | QQ-plot-null.png (file) |  |
37 KB | QQ plot for a null study; from McCarthy et al (2008). | 1 |
| 09:09, 22 July 2010 | QQ-plot-ideal.png (file) |  |
42 KB | QQ plot for an ideal study; from McCarthy et al (2008). | 1 |
| 09:10, 22 July 2010 | QQ-plot-problem.png (file) |  |
46 KB | QQ plot for a problematic study; from McCarthy et al (2008). | 1 |
| 05:46, 7 September 2010 | 666.01.pdf (file) | |
242 KB | Biostatistics 666 Introductory Lecture as of 2010/09/07 | 2 |
| 02:24, 14 September 2010 | 666.02.pdf (file) | |
1.22 MB | 3 | |
| 01:51, 5 October 2010 | 666.09.Master.pdf (file) | |
347 KB | Minor clarification of different uses of N. | 2 |
| 01:51, 5 October 2010 | 666.09.pdf (file) | |
344 KB | Fixes several typos. | 4 |
| 03:53, 7 October 2010 | 666.11.pdf (file) | |
466 KB | Minor typos fixed. | 2 |
| 04:27, 26 October 2010 | 666.13.pdf (file) | |
707 KB | Added a summary slide at the beginning. | 3 |
| 11:07, 9 November 2010 | 666.2010.01.pdf (file) | |
1.49 MB | Lecture on power calculation for genomewide association studies. Also introduces the idea of two stage genomewide association studies. ** Lots of typos fixed in this version ** | 2 |
| 21:02, 2 December 2010 | 666.Zollner.CNV.pdf (file) | |
893 KB | Guest lecture by Sebastian Zollner on Copy Number Variation. | 1 |
| 08:34, 28 September 2011 | 666.05.pdf (file) | |
210 KB | Added frequency spectrum from 12,000 individuals. | 2 |
| 08:35, 28 September 2011 | 666.04.pdf (file) | |
230 KB | Minor typo corrections. | 4 |
| 09:41, 10 October 2011 | 2011.09 - Exome Chip.pdf (file) | |
531 KB | Summary of exome chip design process and content. | 1 |
| 16:40, 31 October 2011 | Pval-qq-sample.png (file) |  |
28 KB | Sample QQ Plot | 1 |
| 02:15, 5 September 2012 | 2011.666.01.pdf (file) | |
824 KB | Yet more minor edits, this time listing potential group projects. | 3 |
| 08:40, 10 September 2012 | 666.03.pdf (file) | |
997 KB | Minor updates. | 6 |
| 23:05, 18 September 2012 | 666.06.pdf (file) | |
779 KB | 4 | |
| 02:25, 26 September 2012 | 666.10.pdf (file) | |
103 KB | Minor tweaks. Now explicitly mentions use of the E-M algorithm to estimate subpopulations and their frequencies or for calling genotype clusters. | 3 |
| 06:16, 3 October 2012 | 666.12.pdf (file) | |
224 KB | Minor edits. | 5 |
| 05:24, 22 October 2012 | 666.2010.02.pdf (file) | |
405 KB | Updated lecture to include example from an actual affected sibling pair study. The lecture is still far too long. | 4 |
| 03:33, 31 October 2012 | 666.16.pdf (file) | |
941 KB | Minor typo fix. | 6 |
| 03:33, 31 October 2012 | 666.17.pdf (file) | |
208 KB | 5 | |
| 06:33, 12 November 2012 | 666.2010.03.pdf (file) | |
1.01 MB | Adds a summary slide. | 5 |
| 00:32, 14 November 2012 | 666.2010.04.pdf (file) | |
1.24 MB | Minor updates, adding Ion Torrent as a sequencing technology and adding some specific numbers to illustrate the scale of genetic variation that can be reached by sequencing. | 3 |
| 02:06, 21 November 2012 | 666.2010.05.pdf (file) | |
503 KB | Minor typo fixes | 3 |
| 02:07, 21 November 2012 | 666.2011.02.pdf (file) | |
689 KB | Minor update; added empirical distribution of read pair distances from QPLOT | 3 |
| 14:58, 28 November 2012 | 666.2011.01.pdf (file) | |
841 KB | Typo fixes. | 4 |
| 04:43, 3 December 2012 | 666.2012.01.pdf (file) | |
505 KB | Added discussion of Lander Waterman results on contig lengths. | 2 |
| 05:22, 3 December 2012 | 666.20.pdf (file) | |
509 KB | This version adds a tiny bit more detail on the use of empirical kinship coefficients. | 5 |
| 09:19, 5 December 2012 | 666.24.pdf (file) | |
124 KB | Minor tweaks | 2 |
| 15:19, 9 January 2013 | Sample-manhattan-plot.png (file) |  |
49 KB | 1 | |
| 15:20, 9 January 2013 | Sample-manhattan-plot-A.png (file) |  |
7 KB | 1 | |
| 15:20, 9 January 2013 | Sample-manhattan-plot-B.png (file) |  |
9 KB | 1 | |
| 15:20, 12 June 2013 | Scott Vrieze.jpg (file) |  |
45 KB | 1 | |
| 12:07, 2 August 2013 | 2013.07 - Overton Award Final.pdf (file) | |
6.86 MB | 1 | |
| 14:29, 25 September 2013 | Question Sheet - Browing and Browning (2012) Am J Hum Genet.pdf (file) | |
83 KB | 1 | |
| 14:32, 25 September 2013 | Question Sheet - Howie et al (2012) Nat Genet.pdf (file) | |
77 KB | 1 | |
| 14:33, 25 September 2013 | Question Sheet - Li et al (2010) Gen Epid.pdf (file) | |
80 KB | 1 | |
| 05:10, 11 October 2013 | Question Sheet - Li et al (2008) Genome Research.pdf (file) | |
101 KB | 1 | |
| 03:58, 7 November 2013 | Question Sheet - Li and Durbin (2009) Bioinformatics.pdf (file) | |
126 KB | Fixed typos in code example. | 2 |
| 04:00, 7 November 2013 | Question Sheet - Zerbino and Birney (2008) Bioinformatics.pdf (file) | |
77 KB | Removed unnecessary second page. | 2 |
