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Date Name Thumbnail Size Description Versions
16:08, 6 December 2013 Question Sheet - Jun et al (2012) American Journal of Human Genetics.pdf (file) 82 KB   1
13:29, 4 December 2013 Question Sheet - Wu et al (2011) American Journal of Human Genetics.pdf (file) 81 KB   1
16:01, 25 November 2013 Question Sheet - Li and Durbin (2011) Nature.pdf (file) 129 KB   1
04:00, 7 November 2013 Question Sheet - Zerbino and Birney (2008) Bioinformatics.pdf (file) 77 KB Removed unnecessary second page. 2
03:58, 7 November 2013 Question Sheet - Li and Durbin (2009) Bioinformatics.pdf (file) 126 KB Fixed typos in code example. 2
05:10, 11 October 2013 Question Sheet - Li et al (2008) Genome Research.pdf (file) 101 KB   1
14:33, 25 September 2013 Question Sheet - Li et al (2010) Gen Epid.pdf (file) 80 KB   1
14:32, 25 September 2013 Question Sheet - Howie et al (2012) Nat Genet.pdf (file) 77 KB   1
14:29, 25 September 2013 Question Sheet - Browing and Browning (2012) Am J Hum Genet.pdf (file) 83 KB   1
12:07, 2 August 2013 2013.07 - Overton Award Final.pdf (file) 6.86 MB   1
15:20, 12 June 2013 Scott Vrieze.jpg (file) 45 KB   1
15:20, 9 January 2013 Sample-manhattan-plot-B.png (file) 9 KB   1
15:20, 9 January 2013 Sample-manhattan-plot-A.png (file) 7 KB   1
15:19, 9 January 2013 Sample-manhattan-plot.png (file) 49 KB   1
09:19, 5 December 2012 666.24.pdf (file) 124 KB Minor tweaks 2
05:22, 3 December 2012 666.20.pdf (file) 509 KB This version adds a tiny bit more detail on the use of empirical kinship coefficients. 5
04:43, 3 December 2012 666.2012.01.pdf (file) 505 KB Added discussion of Lander Waterman results on contig lengths. 2
14:58, 28 November 2012 666.2011.01.pdf (file) 841 KB Typo fixes. 4
02:07, 21 November 2012 666.2011.02.pdf (file) 689 KB Minor update; added empirical distribution of read pair distances from QPLOT 3
02:06, 21 November 2012 666.2010.05.pdf (file) 503 KB Minor typo fixes 3
00:32, 14 November 2012 666.2010.04.pdf (file) 1.24 MB Minor updates, adding Ion Torrent as a sequencing technology and adding some specific numbers to illustrate the scale of genetic variation that can be reached by sequencing. 3
06:33, 12 November 2012 666.2010.03.pdf (file) 1.01 MB Adds a summary slide. 5
03:33, 31 October 2012 666.17.pdf (file) 208 KB   5
03:33, 31 October 2012 666.16.pdf (file) 941 KB Minor typo fix. 6
05:24, 22 October 2012 666.2010.02.pdf (file) 405 KB Updated lecture to include example from an actual affected sibling pair study. The lecture is still far too long. 4
06:16, 3 October 2012 666.12.pdf (file) 224 KB Minor edits. 5
02:25, 26 September 2012 666.10.pdf (file) 103 KB Minor tweaks. Now explicitly mentions use of the E-M algorithm to estimate subpopulations and their frequencies or for calling genotype clusters. 3
23:05, 18 September 2012 666.06.pdf (file) 779 KB   4
08:40, 10 September 2012 666.03.pdf (file) 997 KB Minor updates. 6
02:15, 5 September 2012 2011.666.01.pdf (file) 824 KB Yet more minor edits, this time listing potential group projects. 3
16:40, 31 October 2011 Pval-qq-sample.png (file) 28 KB Sample QQ Plot 1
09:41, 10 October 2011 2011.09 - Exome Chip.pdf (file) 531 KB Summary of exome chip design process and content. 1
08:35, 28 September 2011 666.04.pdf (file) 230 KB Minor typo corrections. 4
08:34, 28 September 2011 666.05.pdf (file) 210 KB Added frequency spectrum from 12,000 individuals. 2
21:02, 2 December 2010 666.Zollner.CNV.pdf (file) 893 KB Guest lecture by Sebastian Zollner on Copy Number Variation. 1
11:07, 9 November 2010 666.2010.01.pdf (file) 1.49 MB Lecture on power calculation for genomewide association studies. Also introduces the idea of two stage genomewide association studies. ** Lots of typos fixed in this version ** 2
04:27, 26 October 2010 666.13.pdf (file) 707 KB Added a summary slide at the beginning. 3
03:53, 7 October 2010 666.11.pdf (file) 466 KB Minor typos fixed. 2
01:51, 5 October 2010 666.09.pdf (file) 344 KB Fixes several typos. 4
01:51, 5 October 2010 666.09.Master.pdf (file) 347 KB Minor clarification of different uses of N. 2
02:24, 14 September 2010 666.02.pdf (file) 1.22 MB   3
05:46, 7 September 2010 666.01.pdf (file) 242 KB Biostatistics 666 Introductory Lecture as of 2010/09/07 2
09:10, 22 July 2010 QQ-plot-problem.png (file) 46 KB QQ plot for a problematic study; from McCarthy et al (2008). 1
09:09, 22 July 2010 QQ-plot-ideal.png (file) 42 KB QQ plot for an ideal study; from McCarthy et al (2008). 1
09:09, 22 July 2010 QQ-plot-null.png (file) 37 KB QQ plot for a null study; from McCarthy et al (2008). 1
10:06, 20 April 2010 666.21.pdf (file) 1.89 MB   2
00:09, 14 April 2010 LocusZoomSmall.png (file) 47 KB   1
00:54, 8 April 2010 666.19.pdf (file) 1.24 MB   3
00:50, 1 April 2010 666.18.pdf (file) 736 KB Introduces the Lander-Green algorithm. 1
07:09, 23 March 2010 666.15.pdf (file) 1.02 MB Shows how a simple disease model can be used to predict IBD probabilities for relative pairs. Introduces possible triangle constraint. 1
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