Uploads by Goncalo

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Date Name Thumbnail Size Description Versions
09:36, 13 November 2017 666.2017.13 - Variance Component Models.pdf (file) 579 KB   1
09:36, 13 November 2017 666.2017.12 - Kinship Coefficients.pdf (file) 329 KB   2
08:49, 11 October 2017 666.2017.10 - Advanced Haplotyping.pdf (file) 644 KB   1
08:36, 9 October 2017 666.2017.09 - Haplotype Estimation.pdf (file) 1.15 MB   1
07:10, 4 October 2017 666.2017.08 - The E-M Algorithm.pdf (file) 212 KB   1
06:48, 2 October 2017 666.2017.07 - Maximum Likelihood Estimation.pdf (file) 1.26 MB   1
08:24, 27 September 2017 666.2017.06 - More Advanced Coalescent Models.pdf (file) 814 KB   1
08:25, 25 September 2017 666.2017.05 - Coalescent and Allele Counts.pdf (file) 421 KB   1
07:51, 13 September 2017 666.2017.03 - Linkage Disequilibrium.pdf (file) 3.31 MB   1
04:44, 11 September 2017 666.2017.02 - Hardy Weinberg Equilibrium.pdf (file) 1.45 MB   1
08:32, 11 September 2017 666.2017.01 - Introductory Lecture.pdf (file) 4.46 MB   1
03:35, 4 December 2017 666.2012.01 - De Novo Assembly.pdf (file) 540 KB   1
04:43, 3 December 2012 666.2012.01.pdf (file) 505 KB Added discussion of Lander Waterman results on contig lengths. 2
02:07, 21 November 2012 666.2011.02.pdf (file) 689 KB Minor update; added empirical distribution of read pair distances from QPLOT 3
14:58, 28 November 2012 666.2011.01.pdf (file) 841 KB Typo fixes. 4
02:06, 21 November 2012 666.2010.05.pdf (file) 503 KB Minor typo fixes 3
00:32, 14 November 2012 666.2010.04.pdf (file) 1.24 MB Minor updates, adding Ion Torrent as a sequencing technology and adding some specific numbers to illustrate the scale of genetic variation that can be reached by sequencing. 3
06:33, 12 November 2012 666.2010.03.pdf (file) 1.01 MB Adds a summary slide. 5
05:24, 22 October 2012 666.2010.02.pdf (file) 405 KB Updated lecture to include example from an actual affected sibling pair study. The lecture is still far too long. 4
08:59, 1 November 2017 666.2010.01 - Power of Genomewide Studies.pdf (file) 930 KB   2
11:07, 9 November 2010 666.2010.01.pdf (file) 1.49 MB Lecture on power calculation for genomewide association studies. Also introduces the idea of two stage genomewide association studies. ** Lots of typos fixed in this version ** 2
05:22, 3 December 2012 666.20.pdf (file) 509 KB This version adds a tiny bit more detail on the use of empirical kinship coefficients. 5
00:54, 8 April 2010 666.19.pdf (file) 1.24 MB   3
00:50, 1 April 2010 666.18.pdf (file) 736 KB Introduces the Lander-Green algorithm. 1
03:33, 31 October 2012 666.17.pdf (file) 208 KB   5
03:33, 31 October 2012 666.16.pdf (file) 941 KB Minor typo fix. 6
07:09, 23 March 2010 666.15.pdf (file) 1.02 MB Shows how a simple disease model can be used to predict IBD probabilities for relative pairs. Introduces possible triangle constraint. 1
07:17, 18 March 2010 666.14.pdf (file) 1.7 MB   1
04:27, 26 October 2010 666.13.pdf (file) 707 KB Added a summary slide at the beginning. 3
06:16, 3 October 2012 666.12.pdf (file) 224 KB Minor edits. 5
03:53, 7 October 2010 666.11.pdf (file) 466 KB Minor typos fixed. 2
02:25, 26 September 2012 666.10.pdf (file) 103 KB Minor tweaks. Now explicitly mentions use of the E-M algorithm to estimate subpopulations and their frequencies or for calling genotype clusters. 3
01:51, 5 October 2010 666.09.pdf (file) 344 KB Fixes several typos. 4
01:51, 5 October 2010 666.09.Master.pdf (file) 347 KB Minor clarification of different uses of N. 2
01:17, 11 February 2010 666.08.pdf (file) 423 KB Advanced guest lecture by Sebastian Zoellner. Focused on computation methods related to the coalescent. February 4, 2010. 1
01:16, 11 February 2010 666.07.pdf (file) 344 KB Advanced lecture on the coalescent by guest lecturer, Sebastian Zoellner. Focused on coalescent modeling with changing population sizes. February 2, 2009. 1
23:05, 18 September 2012 666.06.pdf (file) 779 KB   4
08:34, 28 September 2011 666.05.pdf (file) 210 KB Added frequency spectrum from 12,000 individuals. 2
05:53, 18 September 2017 666.04 - The Coalescent.pdf (file) 785 KB   1
08:35, 28 September 2011 666.04.pdf (file) 230 KB Minor typo corrections. 4
08:40, 10 September 2012 666.03.pdf (file) 997 KB Minor updates. 6
02:24, 14 September 2010 666.02.pdf (file) 1.22 MB   3
05:46, 7 September 2010 666.01.pdf (file) 242 KB Biostatistics 666 Introductory Lecture as of 2010/09/07 2
08:39, 11 April 2017 2017.04 - Adventures in Human Genetics.pdf (file) 9.57 MB   1
05:27, 8 December 2014 2014.12 - Workshop Introduction.pdf (file) 1.51 MB   1
13:05, 12 December 2014 2014.12 - Workshop Closing.pdf (file) 4 MB   1
11:01, 20 June 2014 2014.06 - Workshop Closing.pdf (file) 1,011 KB   1
05:30, 16 June 2014 2014.06 - Abecasis Workshop Introduction.pdf (file) 2.18 MB   1
12:07, 2 August 2013 2013.07 - Overton Award Final.pdf (file) 6.86 MB   1
02:15, 5 September 2012 2011.666.01.pdf (file) 824 KB Yet more minor edits, this time listing potential group projects. 3
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